1.1.1 Pharmacokinetics and Toxicokinetics Contribution Teaching Resources

Evans WE, McLeod HL. Pharmacogenomics Drug disposition, drug targets, and side effects. N Engl J Med 2003;348(6):538-550. (fulltext)

Martin J, Fay M. Cytochrome P450 drug interactions: are they clinically relevant? Australian Prescriber 2001;24(1):10-12. (fulltext)

Albertson TE, Dawson A, de Latorre F, Hoffman RS, Hollander JE, Jaeger A, et al. TOX-ACLS: toxicologic-orientated advanced cardiac life support. Ann Emerg Med Apr 2001;37:S78-S90.

Buckley NA, Whyte IM, Dawson AH. Diagnostic data in clinical toxicology Should we use a Bayesian approach? Clinical Toxicology 2002;40(3):213-222.

American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicology. Position statement: Ipecac syrup. Clinical Toxicology . (fulltext)

American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicology. Position statement: Gastric lavage. Clinical Toxicology .(fulltext)

American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicology. Position statement: Single-dose activated charcoal. Clinical Toxicology .(fulltext) also Multiple dose charcoal

American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicology. Position statement: Whole bowel irrigation. Clinical Toxicology (fulltext)

For a commentary on all of these papers see The revised position papers on gastric decontamination Buckley & Eddleston

Isbister GK, Dawson AH, Whyte IM. Feasibility of prehospital treatment with activated charcoal: Who could we treat, who should we treat? Emerg Med J 2003;20:375-378. (fulltext)

Eddleston M, Juszczak E, Buckley NA, Senarathna L, Mohamed F, Dissanayake W,Hittarage A, Azher S, Jeganathan K, Jayamanne S, Sheriff MR, Warrell DA; Ox-Col Poisoning Study collaborators. Multiple-dose activated charcoal in acute self-poisoning: a randomised controlled trial. Lancet. 2008 Feb 16;371(9612):579-87. (fulltext)

de Silva HA, Fonseka MM, Pathmeswaran A, Alahakone DG, Ratnatilake GA, Gunatilake SB, Ranasinha CD, Lalloo DG, Aronson JK, de Silva HJ. Multiple-dose activated charcoal for treatment of yellow oleander poisoning: a single-blind, randomised, placebo-controlled trial. Lancet. 2003 Jun 7;361(9373):1935-8 (fulltext)

Greene S. Harris C. Singer J. Gastrointestinal decontamination of the poisoned patient. [Review] [78 refs] [Journal Article. Review] Pediatric Emergency Care. 24(3):176-86; quiz 187-9, 2008 Mar.

Roberts D Buckley N Pharmacokinetic considerations in clinical toxicology: clinical applications. Clin Pharmacokinet. 2007;46(11):897-939