====== Drug Binding to Charcoal ======

Activated charcoal is **not effective** in these compounds as they are either not carbon based or are too small to be bound tightly.

   * [[:wikitox:2.2.9.1.2_cyanide|Cyanide]]
  * Ethanol
  * Glycols and esters (e.g. [[:wikitox:2.2.5.2.2_ethylene_glycol|ethylene glycol]])
  * [[:wikitox:2.2.6.8_lead|Heavy metals]]
  * [[:wikitox:2.1.9.6_iron|Iron]]
  * [[:wikitox:2.1.11.9.4_mood_stabilizers|Lithium]]
  * [[:wikitox:2.2.5.2.5_methanol|Methanol]]
  * Strong acids or alkalis

Recent evidence supports some binding of some of these traditionally non-binding compounds.

===== REFERENCES =====

Hoffman RS, Stringer JA, Feinberg RS, Goldfrank LR. Comparative efficacy of thallium adsorption by activated charcoal, Prussian blue, and sodium polystyrene sulfonate. J Toxicol Clin Toxicol 1999; 37(7):833-837 [[http://www.ncbi.nlm.nih.gov/pubmed/10630266|PMID10630266]]

Favin FD, Klein-Schwartz W, Oderda GM, Rose SR. In vitro study of lithium carbonate adsorption by activated charcoal. J Toxicol Clin Toxicol 1988; 26(7):443-450 [[https://www.ncbi.nlm.nih.gov/pubmed/3148035|PMID3148035]]

Gomez HF, McClafferty HH, Flory D, Brent J, Dart RC. Prevention of gastrointestinal iron absorption by chelation from an orally administered premixed deferoxamine/charcoal slurry. Ann Emerg Med 1997; 30(5):587-592 [[https://www.ncbi.nlm.nih.gov/pubmed/9360566|PMID9360566]]