====== 3.3 Pharmacological Basis of Antidote Use ======

Talk by Vincent Danel EAPCCT Seville on prehospital antidote:\\
[[http://curriculum.toxicology.wikispaces.net/space/showimage/antidotes_danel_seville.ppt|Antidotes Danel Seville.ppt [1.8 MB]]]

  * **3.3.1 Antagonize Effects of Poison**
      * 3.3.1.1 Enzyme Inhibitors (eg, [[:wikitox:3.3.1.1.1_physostigmine|physostigmine]])
      * 3.3.1.2 Enzyme Reactivators (eg, pralidoxime)
      * 3.3.1.3 Physiological Antagonists (eg, calcium, [[:wikitox:3.3.1.3.2_glucagon|glucagon]])
      * 3.3.1.4 Receptor Antagonists (eg, atropine, flumazenil, naloxone)
      * 3.3.1.5 Reducing Agent (eg, methylene blue, N-acetylcysteine)

  * **3.3.2 Dispositional Agents**
      * 3.3.2.1 Alcohol Dehydrogenase Antagonists
      * 3.3.2.2 Antivenoms/Antibodies
      * 3.3.2.3 Chelators
      * 3.3.2.4 Cyanide Antidotes
      * 3.3.2.5 Enzyme/Cofactor Replacement (eg, folinic acid, pyridoxine)
      * 3.3.2.6 Oxygen/Hyperbaric Oxygen

  * **3.3.3 Other Antidotes**