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wikitox:decontamination [2025/02/17 00:35] – kharriswikitox:decontamination [2025/02/24 21:23] (current) – kharris
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 Decontamination refers to the techniques that reduce the exposure to a drug or toxin by reducing absorption. As will all actions in clinical toxicology decision to proceed with decontamination should be based on a risk/benefit analysis. Decontamination refers to the techniques that reduce the exposure to a drug or toxin by reducing absorption. As will all actions in clinical toxicology decision to proceed with decontamination should be based on a risk/benefit analysis.
  
-Decontamination should always be a lower priority than patient resusciation.+Decontamination should always be a lower priority than patient resuscitation.
  
 Induced emesis and gastric lavage are techniques that were previously used but are now no longer recommended due to evidence of lower efficacy and higher risk than the other decontamination techniques available. Induced emesis and gastric lavage are techniques that were previously used but are now no longer recommended due to evidence of lower efficacy and higher risk than the other decontamination techniques available.
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 ===== Activated Charcoal ===== ===== Activated Charcoal =====
  
-Porous charcoal has a large surface area that adsorbs most toxins. Most drugs are carbon based and have side chains that may adhere to carbon compounds by either chemical or wek electrostatic forces. It is the preferred method for gastrointestinal decontamination.+Porous charcoal has a large surface area that adsorbs most toxins. Most drugs are carbon based and have side chains that may adhere to carbon compounds by either chemical or weak electrostatic forces. It is the preferred method for gastrointestinal decontamination.
  
 Its effectiveness decreases with time. If given within 30 minutes of ingestion, charcoal may decrease the absorption of the ingested compound by up to 70%, this drops to 35% after 1 hour. Its effectiveness decreases with time. If given within 30 minutes of ingestion, charcoal may decrease the absorption of the ingested compound by up to 70%, this drops to 35% after 1 hour.