Differences
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| wikitox:chloroquine [2018/09/01 09:01] – created - external edit 127.0.0.1 | wikitox:chloroquine [2025/04/13 05:20] (current) – ↷ Links adapted because of a move operation 103.166.41.119 | ||
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| Low potassium is an independent marker for severity in chloroquine overdose. Hypokalaemia occurs rapidly and is likely to relate to an intracellular shift in potassium, perhaps secondary to catecholamine excess or blockade of voltage-gated potassium channels. However, correction of the potassium should be carried out cautiously and there are no data to indicate that this is of benefit (Clemessy et al 1995). | Low potassium is an independent marker for severity in chloroquine overdose. Hypokalaemia occurs rapidly and is likely to relate to an intracellular shift in potassium, perhaps secondary to catecholamine excess or blockade of voltage-gated potassium channels. However, correction of the potassium should be carried out cautiously and there are no data to indicate that this is of benefit (Clemessy et al 1995). | ||
| - | Correction of acidosis and even mild [[:wikitox: | + | Correction of acidosis and even mild [[:concept_serum_alkalinization]] may have a small benefit (Curry et al, 1996) |
| ==== Blood concentrations ==== | ==== Blood concentrations ==== | ||