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wikitox:3.2.1.1.6_hypotension_and_bradycardia [2018/09/01 09:00] – created - external edit 127.0.0.1wikitox:3.2.1.1.6_hypotension_and_bradycardia [2024/05/06 21:48] (current) – removed kharris
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-====== Hypotension and Bradycardia ====== 
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-**There are a relatively small number of toxins that commonly lead to hypotension and bradycardia. It is important to make a correct diagnosis, as these drugs are among the most lethal and have specific antidotes.** 
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-   * [[:wikitox:2.1.6.1.1_calcium_channel_blockers|Calcium channel blocking drugs (CCBs)]] 
-  * [[:wikitox:3.4.3.4.2_beta_blockers|Beta adrenoceptor blocking drugs]] 
-  * [[:wikitox:2.1.6.1.2_cardiac_glycosides|Digoxin]] 
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-In addition there are a number of toxins that will occasionally lead to bradycardia and hypotension in very severe poisoning but which usually cause either tachycardia or no change to heart rate. 
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-  * [[:wikitox:2.1.11.9.4_mood_stabilizers|Lithium]] 
-  * [[:wikitox:2.1.11.9.2.1_tricyclic_antidepressants|Tricyclic antidepressants (TCAs)]] 
-  * [[:wikitox:2.1.11.9.3_antipsychotics|Neuroleptics]] 
-  * [[:wikitox:2.1.11.2_anticonvulsants|Anticonvulsants]] 
-  * [[:wikitox:barbiturates|Barbiturates]] 
-  * [[:wikitox:chloroquine|Chloroquine]] 
-  * [[:wikitox:quinine|Quinine]] 
-  * [[:wikitox:2.1.1.3_opioids|Opioids]] 
-  * [[:wikitox:2.1.11.5.1_acute_management_of_alcohol_problems|Alcohol]] 
-  * [[:wikitox:2.2.7.4.5_organophosphates|Organophosphates]] 
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-Features that help to differentiate between these drugs are: 
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-  * [[:wikitox:response_to_painful_stimuli|RESPONSE TO PAINFUL STIMULI]] 
-  * [[:wikitox:pupil_size_and_reaction|PUPIL SIZE & REACTION]] 
-  * [[:wikitox:myoclonic_jerking_or_hyperreflexia|MYOCLONIC JERKING or HYPERREFLEXIA]] 
-  * [[:wikitox:bowel_sounds|BOWEL SOUNDS]] 
-  * [[:wikitox:ecg_changes|ECG CHANGES]] 
-  * [[:wikitox:response_to_antagonists|RESPONSE TO ANTAGONISTS]] 
-  * [[:wikitox:electrolytes_and_blood_glucose|ELECTROLYTES/BLOOD GLUCOSE]] 
-  * [[:wikitox:blood_concentrations|BLOOD CONCENTRATIONS]] 
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