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wikitox:serotonergic_drug_interactions

Serotonergic Drug Interactions

Any combination of the following drugs may lead to increased serotonergic effects (also see serotonin biosynthesis and metabolism).

L-Tryptophan, S-adenyl-L-methionine, 5-hydroxytryptophan,dopamineSerotonin precursors
SSRIs (citalopram, fluoxetine, fluvoxamine, paroxetine, sertraline), venlafaxine, chlorpheniramineInhibit serotonin reuptake
TCAs (clomipramine, imipramine)Inhibit serotonin reuptake
TramadolInhibit serotonin reuptake
Fenfluramine, p-chloramphetamine, bromocriptine, dihydroergotamine, gepirone, eltoprazin, quipazineSerotonin agonists
MAO Inhibitors (clorgyline, isocarboxazid, nialamide, pargyline, phenelzine, tranylcypromine)Inhibit metabolism of serotonin
RIMAs (brofaramine, befloxatone, toloxatone, moclobemide)Inhibit metabolism of serotonin
LithiumUnknown
Opioids (dextromethorphan, pentazocine, pethidine)Inhibit serotonin reuptake
LSDPartial serotonin agonist
CocaineInhibit serotonin reuptake
Ecstasy (MDMA)Increases serotonin release and inhibits reuptake


wikitox/serotonergic_drug_interactions.txt · Last modified: 2018/09/01 09:01 by 127.0.0.1

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