wikitox:2.1.11.9.4_mood_stabilizers
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wikitox:2.1.11.9.4_mood_stabilizers [2019/07/05 20:26] andrew [Blood concentrations] |
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| The lithium concentration combined with the patients calculated GFR (Glomerular Filtration Rate) can be used to predict the fall in lithium concentration over 36 hours. In chronic lithium toxicity this may help inform the decision to use hemodialysis to enhance elimination. | The lithium concentration combined with the patients calculated GFR (Glomerular Filtration Rate) can be used to predict the fall in lithium concentration over 36 hours. In chronic lithium toxicity this may help inform the decision to use hemodialysis to enhance elimination. | ||
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| The lithium concentration alone should not be used to guide treatment in acute poisoning. Patients with lithium concentrations within the therapeutic range may still be toxic; in particular if their concentrations had been high in the last week. This reflects the slow equilibration of lithium out of the CNS as well as slow restoration of intracellular concentrations. | The lithium concentration alone should not be used to guide treatment in acute poisoning. Patients with lithium concentrations within the therapeutic range may still be toxic; in particular if their concentrations had been high in the last week. This reflects the slow equilibration of lithium out of the CNS as well as slow restoration of intracellular concentrations. | ||
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