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beta_blocker_toxicity [2025/01/07 19:45] – jkohtsbeta_blocker_toxicity [2025/01/07 19:45] (current) – jkohts
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 IV glucagon had been used as antidote for beta-blocker poisoning in the past but its use has been largely superseded by HIET. Glucagon increases intracellular cAMP and activates myosin kinase independent of β-receptors. IV glucagon had been used as antidote for beta-blocker poisoning in the past but its use has been largely superseded by HIET. Glucagon increases intracellular cAMP and activates myosin kinase independent of β-receptors.
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-* 💊 **Glucagon** IV 5-10 mg as a bolus, then an IV infusion titrated against heart rate and blood pressure (starting at 5-10 mg/hour, or the 'reponse dose' per hour).+  * 💊 **Glucagon** IV 5-10 mg as a bolus, then an IV infusion titrated against heart rate and blood pressure (starting at 5-10 mg/hour, or the 'reponse dose' per hour).
  
 **Isoprenaline** \\ **Isoprenaline** \\